Yohimbe side effects, supplement extract, how safe is it? Is there a danger
What are the adverse reactions, safety issues
For a woman, too
November 15 2016

Yohimbe side effects, safety, danger, proper dosage, in men and women
Yohimbe bark has been reported to contain up to 6% total alkaloids, 5 to 15% of which is yohimbine, a drug approved by the FDA for the treatment of erectile dysfunction. Almost all clinical studies have been conducted with yohimbine. For more than 80 years this chemical has been used as a treatment for male and female sexual difficulties. When you take a yohimbe bark supplement, keep the dosage low to avoid side effects which are quite common.

For women, too, works in a female
Yohimbe is often thought of as a therapy for erectile dysfunction in men. Most people don’t realize that it is also effective in women. Women like the enhanced sensation and engorgement of genital organs that it provides.

Herbal combination formulas
To minimize yohimbe side effects but still get the benefits, consider Passion Rx which has several herbs including damiana plant for sexual enhancement along with a potent natural aphrodisiac called Tongkat Ali.

Another option that works well
As an alternative to yohimbe, consider trying another potent aphrodisiac which is an extract of tongkat ali:
Buy LJ100 which works by the second day of use.

buy Yohimbe Bark 500 mg made by Natrol or an effective formula with yohimbe called Passion Rx
Whole Herb Powder Dietary Supplement – not an extract
Supplement Facts: buy Yohimbe powdered bark 500 mg per pill

Directions, how much to take: Take half a yohimbe pill an hour or two before activity. If you are sensitive to herbs, or female, take less than half.

Heart problems, heart rhythm disturbances, cardiac issues
This impotence pill is not recommended for anyone with heart problems or who has heart irregularities. Note: some people with clinical impotence or erectile dysfunction may have underlying heart disease. Be cautious using herbs or drugs for sexual enhancement until a thorough medical evaluation has been done. Another option is Passion Rx which works well with fewer side effects


For more information on erectile dysfunction.

Yohimbe side effects, danger, caution, safety, adverse reactions
Yohimbe should be used cautiously by anyone with a medical condition, particularly those with hypertension, heart disease, diabetes, or those taking medicines, particularly tranquilizers, antidepressants, sedatives, antihistamines, amphetamines or other stimulants, including caffeine. Yohimbine induces noradrenaline secretion. Some of the side effects of yohimbe include anxiety, changes in blood pressure, heart rate increase or palpitations, dizziness, headache, visual disturbances, nausea or abdominal cramps, increased body temperature and sweating.
Since high doses may cause confusion and disorientation, it should not be taken while operating machinery, driving, or performing hazardous activities.

Racing heart, palpitations, testimonial
I decided to try yohimbe well my body went into flight or fight mode felt heart racing and blood pressure wasn’t too high but it was high. I felt ok the rest of the day. That night I didn’t sleep at all and went 4 more days with no sleep also I have been experiencing numerous neurological symptoms such as anxiety, muscle twitches, stiff neck, nausea, dizziness, mild confusion, diarrhea and feeling sick to my stomach. It’s been one week now after consumption and I still feel this way is this normal does it usually take the body a long time to clear it or should I be concerned about this? Any help / advice would be very helpful.
A. The symptoms should be reduced each day that goes on.

Headache and sweating
I wanted to let you know that I get a headache and underarm sweating when I take a full pill.

Cold chills
I am a 73 year-old physician involved in the newer subspecialty of Travel Medicine. I am in excellent health and still have an active sex life. I have had some off and on problems with erectile dysfunction. Over a period of perhaps 10 years, I have had occasion to take yohimbine in one blend or another, always with somewhat unpleasant sensations. The most recent proprietary blend that I tried was a half dose serving of one tablet of Stamina-Rx 550mg over the counter product. Stamina Rx was shown to contain both yohimbine and yohimbe extract. I did have a fairly good response, but with the same side effects as before. The most prominent is a feeling of cold chills up and down my spine and generally over my body. It is most unpleasant and lasts for 8 to 12 hours. I have not seen this indicated in several lists of yohimbe side effects.
A. Yohimbe works well in the right dosage with less side effects, sometimes it takes trial and error to find the least amount of yohimbe that works with the least amount of side effects. In the case of Stamina Rx, perhaps you can try a third of a capsule.


Can I take 25mg of tongkat ali and 100mg of yohimbee together as good libido enhancers, and what about Tribulus Terrestris?
We cannot give specific dosage recommendations or safety since that varies among individuals.

Q. What is the best brand of yohimbe in your opinion. Can it make a penis thicker or increase penis size?
A. There are hundreds of brands on the market and we are not able to test them all. This natural aphrodisiac can increase engorgement of the penis and increase blood flow to it.

Warning: If you are under medical supervision for any condition, consult your healthcare professional before using this product.

The product you have pictured on your website is Natrol Yohimbe bark 500mg capsules. How many milligrams of yohimbine are in each of these 500mg capsules? I can’t find the info anywhere.
We don’t know for sure, but it probably about 1 percent, which would be about 5 mg.

What the Research reveals
Yohimbine has been evaluated in the management of erectile disorder by means of many placebo-controlled trials. This sex pill does appear to have a modest therapeutic benefit, particularly in psychological cases of erectile disorder. In contract, yohimbe has not been studied much. Here’s one summary of a study:
A 1977 German double-blind, placebo-controlled clinical trial of yohimbine hydrochloride included 86 patients with erectile dysfunction and without clearly detectable organic or psychologic causes. Yohimbine was administered orally in a dosage of 30 mg a day (two 5 mg tablets three times daily) for eight weeks. Patients were seen for follow-up after four weeks’ treatment, and for a final visit after eight weeks. Efficacy evaluation was based on both subjective and objective criteria. Subjective criteria included improvement in sexual desire, sexual satisfaction, frequency of sexual contacts, and quality of erection (penile rigidity) during sexual contact/intercourse. Objective criteria of outcome were based on improvement in penile rigidity determined by use of polysomnography in the sleep laboratory. Overall Yohimbine was found significantly more effective than placebo in terms of response rate: 71 vs 45%. Only 7% of patients rated tolerability fair or poor, and most adverse experiences were mild. There was no serious adverse event.

Women and Yohimbe supplement use
A study conducted at the University of Texas at Austin, Texas examined the effects of arginine combined with yohimbine on sexual arousal in postmenopausal women with Female Sexual Arousal Disorder. Twenty-four women participated in three treatment sessions in which self-report and vaginal sexual responses to erotic stimuli were measured following treatment with either L-Arginine (6 g) plus yohimbine (6 mg), yohimbine alone (6 mg), or placebo, using a randomized, double-blind, three-way cross-over design. Sexual responses were measured at approximately 60 minutes postdrug administration. The combined oral administration of L-arginine and yohimbine substantially increased vaginal pulse amplitude responses to the erotic film at 60 min postdrug administration compared with placebo. The vaginal response was measured with an instrument called a vaginal photoplethysmograph.

Mechanism of action, how does it work?
Yohimbine acts through the nervous system to increase blood flow to the genital region. Although many pharmacological properties of yohimbine have been described, at the plasma concentration attained at recommended dosages in humans the predominant activity is antagonism of alpha 2-adrenoceptors.

Effect on kidney function
I found your website, read all the quack stuff, and find your site to be honest. My question: Are the reported dangers of yohimbe to people with renal failure true?

Methods Find Exp Clin Pharmacol. 2003. Endothelin-like action of Pausinystalia yohimbe aqueous extract on vascular and renal regional hemodynamics in Sprague Dawley rats.
The bark of the African tree Pausinystalia yohimbe has been used as a food additive with aphrodisiac and penile erection enhancing properties. The effect of an aqueous extract of P. yohimbe (CCD-X) on renal circulation was assessed in order to test the hypothesis that it possesses additional effects on nitric oxide production and/or endothelin-1 (ET-1)-like actions. In vivo studies with CCD-X in Sprague Dawley rats demonstrated a dose-dependent increase in mean blood pressure and an increase in medullary blood flow (MBF). Both the pressor action and renal medullary vasodilation were blocked by endothelinA (ETA) receptor antagonist BMS182874 and endothelinB receptor antagonist BQ788 in combination. L-Nomega-nitro-l-arginine methyl ester (L-NAME; 10 mg/kg) also inhibited the increase in MBF induced by CCD-X. In vitro studies in isolated perfused kidney and in pressurized renal microvessels confirmed the dose-dependent vasoconstrictor action of this extract. ETA receptor antagonist BQ610 and endothelinB receptor antagonist BQ788 separately and significantly attenuated the renal vasoconstrictor actions of the extract. In addition to the alpha-adrenergic antagonist actions that characterize yohimbine, CCD-X possesses endothelin-like actions and affects nitric oxide (NO) production in renal circulation. These findings suggest a strong possibility of post-receptor cross-talk between alpha2-adrenoceptors and endothelin, as well as a direct effect of alpha2-adrenoceptors on renal NO production.

Effect on thyroid gland or hormones
I have seen some reference to not taking products with yohimbe in them due to its effect on thyroid conditions. What effect does it have on the thyroid gland or thyroid conditions?
We have not seen any specific studies in humans regarding the influence on thyroid gland function. However, this herb and extract should not be used daily, but at most 2 to 3 days a week and as such should not have a major influence on thyroid gland function when used in low or reasonable dosages.

Use by seniors and older individuals
In literature here, you say people over 65 should not take it. I am 79 years old, can’t I take a small amount? I have erectile dysfunction as you probably guessed and have not had sex for about 5 years.
We are not in a position to give individual advice to users of supplements. One person your age could handle a small amount of yohimbe well, another person could have an adverse effect. Your doctor can read the information on this page and make a decision based on your unique situation.

Alkaloids in the bark
What other 31 alkaloids are in yohimbe bark besides yohimbine, and what do they do?
We have not seen any specific or substantial research regarding the different alkaloids in this plant.

Drug testing
Iwas looking to purchase yohimbe bark with yohimbine extract sex herb to enhance male sexual performance. I am currently a citizen of the united states, and my career involves getting drug tested. if i was to buy this specific product, does it contain any type of illegal substance. please give me more information regarding this products legality before I purchase it.
This product does not contain illegal substances, it is a natural herb approved by the FDA and is legal for use in the United States.

I intend to take a sexual enhancement pill along with a yohimbe supplement. I recently purchased a 450mg pill with 2% Yohimbine or 9mg Is this the right dosage?
A. The effective dosage while causing few side effects varies between individuals and the quality of the product and raw material source. A safe way is to start with a small portion of a capsule by itself to learn how it works before even thinking of combining it. Sexual herbs do have side effects when high dosages are taken.

What is the dosage of yohimbe in Passion Rx. Is it recommended as a single use product as we would not like to be taking it regularly. if so, what is the dosage and recommended time to take prior to sexual activity?
In order for yohimbe to have a quick effect within a couple of hours, one has to take a high dose and this leads to unpleasant or serious side effects such as rapid heart beat, increased body temperature, sweating, restlessness, and stomach upset. Passion Rx with yohimbe has a smaller amount to avoid these side effects. But, it does not work right away. The benefits are usually noted on the second, third, or fourth day. It is taken in the morning before breakfast for two days in a row and none the third day, and then resumed the fourth day as needed. Once the effects begin, they last several days even if you don’t take a capsule. The low dose and gradual enhancement are meant to minimize side effects that are common with high dose use. This is a proprietary blend and the dosage of the ingredients cannot be revealed to avoid competitors from copying the successful formula.

If I use it daily, will my body develop a tolerance for it and respond less (sexually libido wise)? Alternately, will I respond more sensitively to it, as if it had a cumulative effect? I seem to have varied and unpredictable responses to this product as I use Passion Rx and it is very nice.
With many sexual herbs tolerance can develop. Less so with yohimbe, it seems to work better, at least for a while, when it is used regularly. There could also be differences in response between people and different dosages and frequency of use could also make a difference.

I have read a few articles that indicate that yohimbe should not be taken by an individual with glaucoma. I am currently taking Prostate Power Rx and Eyesight Rx.
We suggest not using Passion Rx, with or without yohimbe, the same day as Eyesight Rx. These supplements are potent and therefore it is best to not take them the same day.