Rosavin health benefit and research and review
October 12 2016

Rosavin is a substance found in rhodiola species and has health benefits.

Phytochemical and analytical studies of extracts from Rhodiola rosea and Rhodiola quadrifida.
Pharmazie. 2007;
Column chromatography of hydrophiic extracts from Rhodiola rosea and quadrifida led to the isolation of cinnamic alcohol, chlorogenic acid, rhodiooctanoside, rosiridin, rosavin and the phenolic compounds salidroside, rhodiolin and a novel compound consisting of viridoside with an attached arabinose unit (mongrhoside).

Evaluation of biologically active compounds in roots and rhizomes of Rhodiola rosea cultivated in Lithuania.
Medicina. 2007.
Salidroside and rosavins (rosavin, rosarin, and rosin), biologically active compounds of Rhodiola rosea, were analyzed in dried roots and rhizomes of the plants cultivated in Lithuania and naturally growing in Altai geographical region in Russian Federation. Similar amounts of salidroside were found in the extracts, irrespective of the origin of the crude plant; however, the differences in the profile of rosavins were substantial with higher content of total rosavins in the extracts obtained from the plant cultivated in Lithuania (7 vs. 4 mg/mL). It was demonstrated that extracts prepared with 70% (v/v) ethanol contained low concentration of salidroside, while the extraction of rosavins with 70% ethanol was more efficient compared to 40% (v/v) ethanol.

Stress reduction and wellbeing
Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea extract in mice.
Phytother Res. 2007.
Rhodiola rosea, or ‘golden root’, is a popular plant in traditional medicine in Eastern Europe and Asia, with a reputation for improving depression, enhancing work performance, eliminating fatigue and treating symptoms of asthenia subsequent to intense physical and psychological stress. Due to these therapeutic properties, R. rosea is considered to be one of the most active adaptogenic drugs. To confirm and extend results obtained in the few preclinical and clinical studies available in English language journals, the purpose of the present study was to re-investigate the effects produced by a single oral administration of an R. rosea hydroalcohol extract (containing 3% rosavin and 1% salidroside) on the central nervous system in mice. Our results show that this R. rosea extract significantly, but not dose-dependently, induced antidepressant-like, adaptogenic, anxiolytic-like and stimulating effects in mice.

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