Buy DMG supplement pill for mood, immune system improvement, studies
Dimethylglycine sexual effects aphrodisiac pill?
Does it influence the immune system or help autism patients?

November 21 2016

If you find the field of mind-boosting pills, sex nutrients, and anti-aging interesting, you will certainly want to learn more about dimethylglycine, trimethylglycine, and methyl donors. Unless your major is college was chemistry, chances are you don’t remember learning about methyl donors. A methyl donor is simply any substance that can transfer a methyl group [a carbon atom attached to three hydrogen atoms (CH3)] to another substance. Methylation is a biochemical process that is essential to life, health, and regeneration of body cells. Vitamins, hormones, neurotransmitters, enzymes, nucleic acids (DNA and RNA), and antibodies depend on the transfer of methyl groups to complete their synthesis. Scientists suspect that proper methylation of DNA may prevent the expression of harmful genes, such as cancer genes. It’s quite likely that our body’s ability to methylate declines with age, contributing to the aging process, and therefore supplementation may well be beneficial. The research in this area is still very early and no firm answers are yet available.
Some nutrients considered to be methyl donors include TMG. Two of the B vitamins, folic acid and B12, are also considered methyl donors. See additional acetyl-l-carnitine information regarding the use of this natural mind enhancer.

If you want more energy daily, consider an excellent Multivitamin.

Buy DMG Source Naturals 100 mg
I was looking at Source Naturals to buy DMG tablets 125mg, 60 tablets. Are these chewable tablets or tablets that must be swallowed?
These 100 mg tablets by Source Naturals are not chewable.

Where is the Source Natural DMG product manufactured?
In California, USA. N, N-dimethylglycine, is a nutrient common to many grains and meat.

I like to know what is the best form to Dmg and Tmg to take, sublingual or by capsule? I like to know what brand would you consider? If both or avail sublingual?
DMG is available as a sublingual tablet and TMG is available as a capsule. Each person needs to try to see which product works best for their unique physiology.

Dosage, how it is available
I want to buy dmg dosage of 500 mg because of benefits that have been touted in a health magazine article.
We are aware of 100 and 200 mg per pill, but not 500 mg.

Research and benefits
Studies using DMG for autism have generally not found it to be helpful although there are many anecdotes of parents noticing that their autistic children improved by taking it.

Small studies have found that dimethylglycine may help support and boost some aspects of the immune system.

Autoimmune disease
Does research with DMG supplements give any clues whether is is effective in autoimmune disorders?
We have not see such clinical trials.

Multiple sclerosis
I am curious to know if you have known of anyone with positive progressive multiple sclerosis who has had success with the use of DMG supplement. My brother, in his 50s, was diagnosed about 6 years ago. His mobility is declining rapidly and we are looking for anything that may slow the progression. Someone mentioned DMG supplement to me, but I know little about it.
We have not seen any studies using DMG supplements for the treatment of multiple sclerosis.

The Chemistry of DMG and Methyl Donors
Dimethylglycine is basically the amino acid glycine attached to two methyl groups. DMG is a normal physiologically active nutrient found in low levels in such foods as cereal grains, liver, and beans. Humans also naturally produce it in small amounts. As a nutritional supplement, DMG acts as a building block for the synthesis of many important substances such as SAM-e, the amino acid methionine, several hormones, neurotransmitters, and DNA. TMG (trimethylglycine), also known as betaine, is basically the amino acid glycine attached to three methyl groups. Simply, TMG has one more methyl group than DMG.

Side effects, danger, toxicity
I have a friend that thinks taking 9-12 DMG tablets at a time will help with his migraine headaches. Watching him I see that his dizziness increases. Can he get toxic with too much of a good thing at one time?
Side effects do occur and we suggest using less to avoid dizziness or other problems.

Is there an outer limit or toxic dose / toxicity of DMG? Relative to elderly with CHF – what mg range would be recommended?
The best way to find out how DMG supplements will work for anyone is to begin with a low dose, such as 100 mg, for a week and then base future dosage on the initial response. Elderly individuals are less tolerant to supplements and can get side effects on lower dosages.

Interactions with other dietary supplements
Q. I plan to take an herbal formula with yohimbe bark and wanted to know if there were dmg studies testing this combination.
A. Both yohimbe and DMG have a quick onset of effects and we suggest not mixing them together.

I found an article about Prozac and the autoimmune system. I was diagnosed with amyopathic dermatomiositis about 4 yrs ago. I take 60 mg of Prozac, 200 mg of Provigil for narcolepsy, and 10 mg of lisinopril for high blood pressure. I’m also starting a prescription drug for high cholesterol and one to enhance bone density. Will dimethylglycine interfere with any of these drugs? I read an article that stated it would help with my autoimmune disease. I no longer have the rash and I wear sunscreen and sun-protective clothing but I am terrified I will get the rash again. I am very active outdoors in the summer; swimming, hiking, power walking, biking, and tennis. I want to be able to continue those activities and not be worried all the time.
It is not easy to predict the interactions between supplements and a medication, let alone several medications.

Dialysis patients, kidney disease
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations. Departments of Nephrology, Clinical Biochemistry, and Pathology, Christchurch Hospital, Christchurch, New Zealand. Dr David McGregor, Department of Nephrology, Christchurch Hospital, Private Bag 4710 Christchurch, New Zealand.
Hyperhomocysteinemia is a risk factor for atherosclerosis that is common in chronic renal failure, but its cause is unknown. Homocysteine metabolism is linked to betaine-homocysteine methyl transferase (BHMT), a zinc metalloenzyme that converts glycine betaine to N,N dimethylglycine. DMG is a known feedback inhibitor of BHMT. We postulated that DMG might accumulate in CRF and contribute to hyperhomocysteinemia by inhibiting BHMT activity. We find DMG accumulates in CRF and independently predicts plasma tHcy concentrations. These findings suggest that reduced BHMT activity is important in the pathogenesis of hyperhomocysteinemia in CRF.